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Written by ANI
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Thursday, 23 October 2008 |
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Washington, Oct 23 (ANI): Researchers from University of Minnesota have identified certain genetic variations that may help predict survival in cancer patients. A research team led by Brian Van Ness, Ph.D, from Masonic Cancer Centre, University of Minnesota, claim to have identified combinations of genes associated with early clinical relapse of multiple myeloma, a cancer of the white blood cells that produce antibodies, which can help predict patient's response to treatment. "Ultimately, the goal of this research is to predict drug efficacy and toxicity based on a patient's genetic profile, and develop individualized assessments and predictions for the right drug, at the right dose, for the right patient," said Van Ness. "This approach offers the dual benefits of avoiding unnecessary treatment for patients less likely to respond to a particular drug, and targeting treatments to those who will benefit most," he added. For the study, Van Ness and his colleagues analysed the genetic information that the International Myeloma Foundation has gathered from myeloma patients worldwide through its program, Bank On A Cure(r). "Although myeloma is considered a fatal disease, individual patients have widely varied rates of disease progression and response to treatment because of attributes encoded in their DNA," said Van Ness. According to Van Ness, the research study findings demonstrate that cancer outcomes differ because patients vary in the ways they absorb, distribute, metabolize, and transport drugs across cell membranes. Individual variations in genes that regulate these biologic processes may not only affect the effectiveness of the drug, but also can result in adverse side effects. The findings are reported in the current issue of the research journal BMC Medicine. (ANI)
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Last Updated ( Thursday, 23 October 2008 )
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Written by ANI
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Thursday, 23 October 2008 |
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London, Oct 23 (ANI): Thousands of tiny gold pins which lay hidden in a desk drawer for 40 years have been described as one of Britain's most important archeological finds. According to a report in the Telegraph, the artifacts were part of a dagger buried with a warrior chief, near Stonehenge, nearly 4,000 years ago. The pinhead-sized studs form an intricate pattern on the handle of the dagger, but archeologists failed to realise their significance when they excavated the burial mound in Wiltshire - known as Bush Barrow- in 1808. Now, they are to be re-united with other priceless artifacts unearthed at the site and put on show at the Wiltshire Heritage Museum in Devizes after Niall Sharples, a senior lecturer at Cardiff University turned out his predecessors' desk and discovered them in a film canister labelled Bush Barrow. In the 1960s, the gold was taken away for examination by Professor Richard Atkinson, a Cardiff University archaeologist well known for his work at Stonehenge and nearby Silbury Hill. "We think he recognized what they were but then he died and they were rescued by his successor Professor John Evans who put them in a drawer in his desk," said Wiltshire Heritage Museum director David Dawson. "Professor Evans died in 2005 and the gold studs have now been found by Niall Sharples, who is going to return them to us," he added. The gold pins, thought to come from Ireland, were fashioned by craftsmen in Brittany, France, and inlaid in an intricate herringbone pattern into the handle of the ceremonial dagger, which had an eight inch bronze blade. It is the richest and most important Bronze Age grave on the Salisbury Plain and in Britain, according to experts. According to David Dawson, the director of Wiltshire Heritage Museum, "It's an unbelievable find". "The gold studs are remarkable evidence of the skill and craftsmanship of Bronze Age goldsmiths - quite rightly described as 'the work of the gods'," he added. (ANI)
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Last Updated ( Thursday, 23 October 2008 )
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Written by ANI
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Thursday, 23 October 2008 |
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New Delhi, Oct 23 (ANI): Paris Hilton has bought an estate worth 850000 dollars in London, but the estate has a mottled history, as it has been a former brothel and a haven for drug peddlers and pirates. Hilton, who is currently filming her reality show My BBF in London, stated that the estate has exquisite architecture, reports China Daily. "It's just beautiful. It doesn't have regular rooms but is more like a maze.It used to be an opium den and still has iron joists where pirates and thieves were shackled to the wall," Hilton said. "Paris really appreciated the quirkiness of the place - and the knockdown price for such a unique building - and immediately put in an offer, a source told Daily Star. (ANI)
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Last Updated ( Thursday, 23 October 2008 )
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Written by ANI
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Friday, 24 October 2008 |
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Sydney, Oct 24 (ANI): The Australian Federal Police (AFP) have reportedly passed the obligation of charging Dr Mohamed Haneef with terrorism on to the Commonwealth Director of Public Prosecutions (CDPP). In a submission to the Clarke inquiry into the case, the AFP said that while the decision to charge Dr Haneef ultimately rested with it, the CDPP's legal advice was "a fundamental factor" in the decision-making process to charge Dr Haneef. The police submission further said the decision to drop the charge against Dr Haneef 11 days later was also taken by the Commonwealth Director of Public Prosecutions. "Prior to the receipt of the advice from the CDPP, the AFP was of the view that there was not enough evidence to charge," The Age quoted the AFP as saying. But, the AFP's submission contrasts with the CDPP's submission made to the inquiry in August, which had that the police had pressured a prosecutor for reassurance that Dr Haneef could be charged. The key period under dispute is between July 12 last year, when the AFP started briefing Commonwealth prosecutors on possible charges, and July 14, when Dr Haneef was charged. The police submission had conceded that on July 12, the AFP incorrectly told the prosecutors that a mobile phone SIM card belonging to Dr Haneef was found in the possession of Kafeel Ahmed, who was arrested at the site of a failed terrorist attack at Glasgow airport. But it said they issued a correction the next day after receiving fresh information from the British police that the card was in the possession of another man. They say the updated advice was included in a 49-page written brief that Commonwealth prosecutors studied for several hours on July 13, but that the prosecutors still advised that there was sufficient evidence to charge Dr Haneef. And, Dr Haneef was charged the next day. The police submission said that the prosecutors made two incorrect statements to the court when charging Dr Haneef, including the whereabouts of Dr Haneef's SIM card. They said that they were not in court, and, so, were not in an immediate position to correct the prosecutors, and only found out about the incorrect statements through the media. (ANI)
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Last Updated ( Friday, 24 October 2008 )
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Written by ANI
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Friday, 26 September 2008 |
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New Delhi, Sept 26 (ANI): In a last-ditch effort to salvage the Nano car project, West Bengal Chief Minister Buddhadeb Bhattacharjee has written to Tata Group Chairman Ratan Tata urging him not to shift the project from Singur. Bhattacharjee in his letter to Ratan Tata said no more disruptions would occur. "We assure you of police protection," he said. The West Bengal Government is awaiting Ratan Tata's response. West Bengal Industries Minister Nirupam Sen said, "The state government is trying its best to retain the Nano project in Singur." The letter was sent after Thursday's decision at the state cabinet meeting to appeal to both the Tatas to implement the project here as well as to the opposition to cooperate in the interest of the state. Trinamool Congress (TMC), on Thursday, said it was willing for further talks on Singur issue if the West Bengal Governor Gopalkrishna Gandhi takes an initiative. Trinamool Congress did not ask the Tata Motors to leave Singur, said the TMC chief Mamata Banerjee, and added, "Let both agriculture and industry smile." She said the state government and Communist Party of India (Marxist) were claiming that the September 7 agreement was a 'declaration' and not an accord. "They are cheating us. They have also insulted the Governor by violating the agreement", she charged. While reading out the copy of 'agreement', Banerjee said that the TMC was ready for a 'land-based solution'. Meanwhile truckloads of material have started rolling out of the Singur Nano factory, a sign that Tata Motors is on an exit route from West Bengal. However, there has been no formal communication from the company so far. Trouble began after the West Bengal government acquired 1000 acres of farmland for the Tata Motors 'Nano' small car plant at Singur last year. The government offered compensation, which some farmers rejected and the state's main opposition TMC has been demanding that at least 400 acres be returned to farmers. The government says it is in favour of a land-based solution for farmers but was against disturbing the Tata Motors plant site. (ANI)
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Last Updated ( Friday, 26 September 2008 )
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